Univerzita Pardubice Fakulta chemicko- technologická

Univerzita Pardubice

Zaměstnanci
|
Studenti
English

Publikace detail

Pneumatic valves for micro-milled microfluidic devices

Autoři: Novotný Jakub | Foret František

Rok: 2017

Druh publikace: ostatní - přednáška nebo poster

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Pneumatic valves for micro-milled microfluidic devices	There are many approaches for flow manipulation and integration of valves for use with miniaturized systems. From piezoelectric valves, through pressure-sensitive hydrophobic barriers to Quake valves in elastomeric microchips. Of course, different materials and fabrication methods may be more suitable for some options and restrict the use of different ones. Micro-milling in plastics using CNC devices is a popular microfabrication technique for creating casting masters and/or devices with larger channels. While convenient not only for fabrication of the microfluidic components but also construction of other auxiliary components and accessories, creation of some of the integrated segments typical for microfluidic devices may be a challenge. Geometry and sizes of the available cutting tools and precision of the CN control and of the machine set limits on the possible design of the microfluidic device and on utilization of some of the microfluidic phenomena. In this work we have focused on micro-milling of polycarbonate system integrating microreactors, reagent mixing, trapping column and elution for sample preparation prior to optical/electrochemical detection. Utilizing CNC router, microfluidic channel was milled using a 400 μm flat-end mill. Flow manipulation and input and output control was realized by interrupting branches of the microfluidic channel using pneumatic valves based on an elastic membrane. First, we have tested valves of the well-known Quake design, actuated by air pressure applied to a chamber, separated from the microfluidic channel by a thin membrane. We have found that this approach was not suitable for large volume channels where the membrane often collapsed the whole microfluidic channel. This poster presentation describes an alternative solution using a pneumatically actuated mechanical membrane switch.	Pneumatic; valves; micro-milled; microfluidic; devices