Publikace detail

Interaction between the API and excipients in solid state dosage form prepared by direct compression method

Autoři: Romanová Jana | Svoboda Roman | Komersová Alena | Pekárek T

Rok: 2018

Druh publikace: ostatní - článek ve sborníku

Název zdroje: 13th International Conference on Solid State Chemistry : book of abstracts

Název nakladatele: Univerzita Pardubice

Místo vydání: Pardubice

Strana od-do: 168-168

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Interaction between the API and excipients in solid state dosage form prepared by direct compression method	the objective of this study is to clarify the possible interaction between SA and excipients. teh mixture of SA and excipients was examined over the time by using differential scanning calorimetry, infrared spectrocopy and Raman mapping. presence of the interaction was confirmed based on the occurence of eutectic melting peak on the calorimetric signal. true nature of the interaction will be discussed based on the spectroscopic data.	Interaction; API; excipient; salicylic acid; Kollidon; sustained release

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