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Publikace detail

Interaction between the API and excipients in solid state dosage form prepared by direct compression method
Autoři: Romanová Jana | Svoboda Roman | Komersová Alena | Pekárek T
Rok: 2018
Druh publikace: ostatní - článek ve sborníku
Název zdroje: 13th International Conference on Solid State Chemistry : book of abstracts
Název nakladatele: Univerzita Pardubice
Místo vydání: Pardubice
Strana od-do: 168-168
Tituly:
Jazyk Název Abstrakt Klíčová slova
eng Interaction between the API and excipients in solid state dosage form prepared by direct compression method the objective of this study is to clarify the possible interaction between SA and excipients. teh mixture of SA and excipients was examined over the time by using differential scanning calorimetry, infrared spectrocopy and Raman mapping. presence of the interaction was confirmed based on the occurence of eutectic melting peak on the calorimetric signal. true nature of the interaction will be discussed based on the spectroscopic data. Interaction; API; excipient; salicylic acid; Kollidon; sustained release