Univerzita PardubiceFakulta chemicko- technologická

Univerzita Pardubice

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Voltammetric behavior of anti-inflammatory drugs from oxicam class

Autoři: Šelešovská Renáta | Hlobeňová Frederika | Mandincová Martina | Skopalová Jana | Janíková Lenka | Chýlková Jaromíra

Rok: 2019

Druh publikace: ostatní - článek ve sborníku

Strana od-do: nestránkováno

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Voltammetric behavior of anti-inflammatory drugs from oxicam class	Oxicam drugs are a group of structurally closely related substances with anti-inflammatory, analgesic and antipyretic activities [1]. In this work, voltammetric behavior of four representatives of this group, namely meloxicam, lornoxicam, piroxicam, and tenoxicam (Figure 1), was studied using boron doped diamond electrode (BDDE). This electrode was applied due to its specific electrochemical properties, especially the wide potential window allowing the observation of signals at about very positive potential values [2-4]. Mechanism of the electrochemical oxidation was investigated with high performance liquid chromatography-mass spectrometry analysis of analytes solutions electrolyzed on carbon fiber brush electrode [5]. Finally, voltammetric methods for all the above-mentioned drugs were developed and applied for real samples analysis.