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Publikace detail

Electrochemical impedance spectroscopy for the quantitative determination of drugs.
Rok: 2023
Druh publikace: ostatní - článek ve sborníku
Název zdroje: ChemZi
Název nakladatele: Slovenská chemická spoločnosť pri SAV
Místo vydání: Bratislava
Strana od-do: 132
Tituly:
Jazyk Název Abstrakt Klíčová slova
eng Electrochemical impedance spectroscopy for the quantitative determination of drugs. Electrochemical methods have emerged as valuable tools for drug analysis due to their sensitivity, selectivity, and potential for quantitative determination. Voltammetric methods offer several advantages in drug analysis, including their ability to provide information on drug redox properties, kinetics, and stability [1]. Among these techniques, electrochemical impedance spectroscopy (EIS) has gained prominence for its ability to probe the electrochemical behavior of drug molecules in solution [2]. By leveraging the principles of EIS, which involves measuring the impedance response of an electrochemical system as a function of frequency, valuable insights into drug concentration can be obtained. Changes in the drug concentration can induce variations in the impedance spectrum, including resistance, capacitance, and inductance, which can be correlated to the drug concentration [2]. In this work, we will compare the classical voltammetric analysis with electrochemical impedance spectroscopy (EIS) for determining the concentration of substances. By investigating the dependency of relevant parameters on concentration, we will demonstrate how the classical voltammetric method and EIS can be utilized for the quantitative determination of substance concentration. Our investigation will contribute to understanding the advantages and limitations of each technique and their potential for accurate and sensitive determination of substance concentration in different systems.