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A new approach to determining the drug guaifenesin using voltammetric and flow injection analysis
Autoři: Kelíšková Pavlína | Matvieiev Oleksandr | Sokolová Romana | Janíková Lenka | Behúl Miroslav | Šelešovská Renáta
Rok: 2024
Druh publikace: ostatní - článek ve sborníku
Název zdroje: 43rd Modern Electrochemical Methods :Proceedings of the International Conference
Název nakladatele: BEST Servis
Místo vydání: Ústí nad Labem
Strana od-do: 96-100
Tituly:
Jazyk Název Abstrakt Klíčová slova
eng A new approach to determining the drug guaifenesin using voltammetric and flow injection analysis This study presents a new method for detecting guaifenesin (GFE) in pharmaceutical samples. We employed screen-printed sensors with a boron-doped diamond electrode (BDDE) to develop and validate both voltammetric and flow injection analysis with electrochemical detection (FIA-ED) methods. These approaches were effectively used to analyze model solutions, pharmaceutical preparations, and serum samples spiked with GFE, producing accurate results comparable to those obtained with HPLC/DAD analysis. The developed methods provide straightforward, sensitive, and selective means for determining GFE in various sample matrices, underscoring the potential of SP/BDDE in electrochemical analysis. Guaifenesin, Screen-printed sensor, Boron-doped diamond electrode, Voltammetry, Flow-injection analysis, Pharmaceutical preparations.