Publikace detail

Antimicrobial Testing of Potential Materials in Healthcare

Autoři: Stará Ivana | Brožková Iveta | Pejchalová Marcela | Burgert Ladislav

Rok: 2023

Druh publikace: ostatní - článek ve sborníku

Název zdroje: Conventional and alternative approaches combating antimicrobial resistance

Název nakladatele: Univerzita Komenského v Bratislave

Místo vydání: Bratislava

Strana od-do: 28

Tituly:

Jazyk	Název	Abstrakt	Klíčová slova
eng	Antimicrobial Testing of Potential Materials in Healthcare	Non‐healing wounds are a serious social and economic problem for patients worldwide [1]. A biopolymer for wound dressing applications such as hyaluronic acid (HA) has a supportive effect in wound care [2]. In the present study, we focus on the antimicrobial activity of materials from staple microfibers of hyaluronic acid and oxidized starch in combination with acidifying compounds or with the addition of silver. We determined the diameter of the inhibition zones around the sample. The sensitivity of selected bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus) and yeast (Candida albicans) to the tested materials is also determined. For antimicrobial susceptibility testing, we use an agar diffusion assay. The evaluation of this test is based on the ability of the covering materials to inhibit bacterial growth under and around the sample. The results of this study suggest that HA-starch-based materials with acidifying addition may prove beneficial in minimizing bacterial contamination of wounds.	antimicrobial activity; hyaluronic acid; starch; materials in healthcare

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